MI Compendium of Systematic Reviews

Minimum Intervention (MI) in Dentistry

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or SWITCH SEARCH: Comparison of MI related aspects between selected dental materials

You searched: Xylitol (Sugar-free chewing gum)

Systematic Reviews

The impact of polyol-containing chewing gums on dental caries: a systematic review of original randomized controlled trials and observational studies.
Reference: J Am Dent Assoc. 2008 Dec;139(12):1602-14.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19047666

Dietary factors in the prevention of dental caries: a systematic review.
Reference: Acta Odontol Scand. 2003 Dec;61(6):331-40.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/14960004

Caries preventive effects of xylitol-based candies and lozenges: a systematic review.
Reference: J Public Health Dent. 2011 Spring;71(2):117-24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21774134

Xylitol as a prophylaxis for acute otitis media: systematic review.
Reference: Int J Audiol. 2010 Oct;49(10):754-61.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20874048

Anticariogenic effect of xylitol versus fluoride – a quantitative systematic review of clinical trials
Reference: Int Dent J 2012; 62: 6-20
Abstract: http://onlinelibrary.wiley.com/doi/10.1111/j.1875-595X.2011.00086.x/abstract

Effect of xylitol versus sorbitol: a quantitative systematic review of clinical trials
Reference: Int Dent J 2012; DOI: 10.1111/j.1875-595X.2011.00113.x
Abstract: http://onlinelibrary.wiley.com/doi/10.1111/j.1875-595X.2011.00113.x/abstract

Preventing dental caries in children <5 years: systematic review updating USPSTF recommendation.
Reference: Pediatrics. 2013 Aug;132(2):332-50. doi: 10.1542/peds.2013-1469. Epub 2013 Jul 15.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/23858419

Xylitol-containing products for preventing dental caries in children and adults.
Reference: Cochrane Database Syst Rev. 2015 Mar 26;3:CD010743.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/?term=Xylitol-containing+products+for+preventing+dental+caries+in+children+and+adults.

Effect of maternal use of chewing gums containing xylitol on transmission of mutans streptococci in children: a meta-analysis of randomized controlled trials.
Reference: Int J Paediatr Dent. 2015 Feb 13. doi: 10.1111/ipd.12155. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/?term=Effect+of+maternal+use+of+chewing+gums+containing+xylitol+on+transmission+of+mutans+streptococci+in+children%3A+a+meta-analysis+of+randomized+controlled+trials.

Xylitol in preventing dental caries: A systematic review and meta-analyses.
Reference: J Nat Sci Biol Med. 2017 Jan-Jun;8(1):16-21.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28250669

Published Commentary

Consistent evidence to support the use of xylitol- and sorbitol-containing chewing gum to prevent dental caries.
Reference: Evid Based Dent. 2009;10(1):10-1.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19322219

Polyol-containing chewing gums: flawed evidence.
Reference: Evid Based Dent. 2009;10(2):36; author reply 36.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19561570

Chewing gum and caries.
Reference: J Am Dent Assoc. 2009 Jun;140(6):638, 640; author reply 640.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19491155

Limited evidence on the anticavity effect of polyol chewing gum
Reference: ADA. Center for Evidence-Based Dentistry
Abstract: http://ebd.ada.org/SystematicReviewSummaryPage.aspx?srId=81b3eb5a-e603-4bc7-94e3-d8a1137fdb5a&IndexId=5866d296-fc17-4613-b65c-6c86d12c408b

Dietary factors and dental caries.
Reference: Evid Based Dent. 2005;6(1):7-8.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/15789040

Caries prevention.
Reference: Acta Odontol Scand. 2004 Apr;62(2):116; author reply 117.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/15198394

Current controversies--is there merit?
Reference: Adv Dent Res. 2009;21(1):48-52.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19717410

Extent and quality of systematic review evidence related to minimum intervention in dentistry: essential oils, powered toothbrushes, triclosan, xylitol
Reference: Int Dent J 2011; 61: 179-92.
Abstract: http://onlinelibrary.wiley.com/doi/10.1111/j.1875-595X.2011.00055.x/abstract

Weak evidence of caries reduction using xylitol-based lozenges in two of three selected studies
Reference: Evidence-Based Dentistry (2012) 13, 7–8. doi:10.1038/sj.ebd.6400836
Abstract: http://www.nature.com/ebd/journal/v13/n1/abs/6400836a.html

Systematic Review Updates
Further Clinical Information

Treatment protocols: nonfluoride management of the caries disease process and available diagnostics.
Reference: Dent Clin North Am. 2010 Jul;54(3):527-40.
Abstract: Dent Clin North Am. 2010 Jul;54(3):527-40.

An end to crossover designs for studies on the effect of sugar substitutes on caries?
Reference: Caries Res. 2009;43(5):331-3. Epub 2009 Aug 1.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19648742

Xylitol as caries prevention?
Reference: Caries Res. 2010;44(2):170; author reply 170. Epub 2010 May 5.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20453507

End to crossover designs for studies on the effect of sugar substitutes?
Reference: Caries Res. 2010;44(2):169; author reply 170. Epub 2010 May 5.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20453506


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