MI Compendium of Systematic Reviews

Minimum Intervention (MI) in Dentistry

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You searched: CPP-ACP (Tooth remineralisation)

Systematic Reviews

Caries preventive effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP): a meta-analysis.
Reference: Acta Odontol Scand 2009; 21: 1-12.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19701818

Clinical efficacy of casein derivatives: a systematic review of the literature.
Reference: J Am Dent Assoc. 2008 Jul;139(7):915-24
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/18594077

Effect of remineralizing agents on white spot lesions after orthodontic treatment: a systematic review.
Reference: Am J Orthod Dentofacial Orthop. 2013 Mar;143(3):376-382.e3. doi: 10.1016/j.ajodo.2012.10.013.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/?term=Chen+H%2C+Liu+X%2C+Dai+J%2C+Jiang+Z%2C+Guo+T%2C+Ding+Y.

Long-term remineralizing effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on early caries lesions in vivo: A systematic review.
Reference: J Dent. 2014 Apr 3. pii: S0300-5712(14)00096-7. doi: 10.1016/j.jdent.2014.03.015. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24705069

Prevention and Treatment of White Spot Lesions During and After Treatment with Fixed Orthodontic Appliances: a Systematic Literature Review.
Reference: J Oral Maxillofac Res. 2016 Jun 30;7(2):e1
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27489605

Is there a place for Tooth Mousse in the prevention and treatment of early dental caries? A systematic review.
Reference: BMC Oral Health. 2015 Sep 25;15(1):113.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26408042

Minimally Invasive Treatment of White Spot Lesions--A Systematic Review.
Reference: Oral Health Prev Dent. 2016;14(3):197-205.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26973988

Non-surgical treatment of dentin caries in preschool children--systematic review.
Reference: BMC Oral Health. 2015 Apr 3;15:44.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25888484

Published Commentary

Casein phosphopeptide-amorphous calcium phosphate shows promise for preventing caries.
Reference: Evid Based Dent. 2010;11(1):11-2.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20348890

Preliminary evidence suggests remineralizing effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)
Reference: ADA Centre for EBD
Abstract: http://ebd.ada.org/SystematicReviewSummaryPage.aspx?srId=6d74d1df-46b6-4650-b350-cde47305cbcd#

Lack of reliable evidence of the effectiveness of remineralising agents for the treatment of post orthodontic white spot lesions
Reference: Evidence-Based Dentistry (2013) 14, 76–77. doi:10.1038/sj.ebd.6400949
Abstract: http://www.nature.com/ebd/journal/v14/n3/abs/6400949a.html?WT.ec_id=EBD-201309

Systematic Review Updates
Further Clinical Information

A closer look at remineralisation and CPP-ACP
Reference: J Minim Interv Dent 2010; 3 (4): 148 - 151
Abstract: http://www.mi-compendium.org/e-3-4-2.pdf

Combined CPP-ACP and photoactivated disinfection (PAD) therapy in arresting root surface caries: a case report.
Reference: Br Dent J. 2007 Oct 27;203(8):457-9.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/17965683

Minimally invasive treatment of white spot enamel lesions.
Reference: Quintessence Int. 2007 Sep;38(8):633-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/17823680

Considering biomodification and remineralization techniques as adjuncts to vital tooth-bleaching regimens.
Reference: Compend Contin Educ Dent. 2007 May;28(5):234-6, 238-40.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/17607888


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