MI Compendium of Systematic Reviews

Minimum Intervention (MI) in Dentistry
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Systematic Reviews

The caries-preventive effect of chlorhexidine varnish in children and adolescents: a systematic review.
Reference: Caries Res. 2010;44(4):333-40.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20606432

Chlorhexidine varnish for preventing dental caries in children, adolescents and young adults: a systematic review.
Reference: Eur J Oral Sci. 2006 Dec;114(6):449-55.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/17184224

Essentials Oils** Compared to Chlorhexidine With Respect to Plaque and Parameters of Gingival Inflammation: A Systematic Review.
Reference: J Periodontol. 2010 Nov 2. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21043801

Caries-inhibiting effect of preventive measures during orthodontic treatment with fixed appliances. A systematic review.
Reference: Caries Res. 2004 Sep-Oct;38(5):413-20.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/15316184

Rinsing with chlorhexidine gluconate solution after brushing and flossing teeth: a systematic review of effectiveness.
Reference: Quintessence Int. 2006 Sep;37(8):605-12.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/16922019

The effect of chlorhexidine varnish on root caries: a systematic review.
Reference: Caries Res. 2011;45(2):162-73.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21525751

The efficacy of 0.12% chlorhexidine mouthrinse compared with 0.2% on plaque accumulation and periodontal parameters: a systematic review.
Reference: J Clin Periodontol. 2010 Sep;37(9):829-39.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed?term=The%20efficacy%20of%200.12%25%20chlorhexidine%20mouthrinse%20compared%20with%200.2%25%20on%20plaque%20accumulation%20and%20periodontal%20parameters%3A%20systematic%20review.

Chlorhexidine for the prevention of alveolar osteitis
Reference: Int J Oral Maxillofac Surg 2012;10.1016/j.ijom.2012.04.017
Abstract: http://www.sciencedirect.com/science/article/pii/S0901502712001749

Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review.
Reference: J Clin Periodontol. 2012 Nov;39(11):1042-55.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/?term=Van+Strydonck+DA%2C+Slot+DE%2C+Van+der+Velden+U%2C+Van+der+Weijden+F.

The efficacy of chlorhexidine dentifrice or gel on plaque, clinical parameters of gingival inflammation and tooth discoloration: a systematic review.
Reference: Int J Dent Hyg. 2013 Aug 29. doi: 10.1111/idh.12050. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24034716

Systematic review of basic oral care for the management of oral mucositis in cancer patients.
Reference: Support Care Cancer. 2013 Sep 10. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24018908

Systematic Review on Noninvasive Treatment of Root Caries Lesions.
Reference: J Dent Res. 2014 Nov 14. pii: 0022034514557330. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25398366

Chlorhexidine treatment for the prevention of dental caries in children and adolescents.
Reference: Cochrane Database Syst Rev. 2015 Apr 13;4:CD008457. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25867816

The effect of chlorhexidine dentifrice or gel versus chlorhexidine mouthwash on plaque, gingivitis, bleeding and tooth discoloration: a systematic review.
Reference: Int J Dent Hyg. 2015 May;13(2):83-92.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25059640

Effects of chlorhexidine varnish on caries during orthodontic treatment: a systematic review and meta-analysis.
Reference: Braz Oral Res. 2016 Nov 28;30(1):e115.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27901199

The antimicrobial effect of chlorhexidine varnish on mutans streptococci in patients with fixed orthodontic appliances: a systematic review of clinical efficacy.
Reference: Int J Dent Hyg. 2016 Feb;14(1):53-61.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26257398

Published Commentary

Little evidence exists about optimal caries-prevention strategies during orthodontic treatment.
Reference: Evid Based Dent. 2004; 5: 97.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/15608709

Effectiveness of chlorhexidine varnish for preventing caries uncertain
Reference: Evid Based Dent. 2010; 11: 108
Abstract: http://www.nature.com/ebd/journal/v11/n4/abs/6400754a.html

Limited evidence of the effect of chlorhexidine varnish (CHX-V) on root caries
Reference: Evidence-Based Dentistry (2011) 12, 39–40.
Abstract: http://0-www.nature.com.innopac.wits.ac.za/ebd/journal/v12/n2/abs/6400787a.html

No difference between 0.12% and 0.2% chlorhexidine mouthrinse on reduction of gingivitis
Reference: Evidence-Based Dentistry (2011) 12, 8-9
Abstract: http://www.nature.com/ebd/journal/v12/n1/pdf/6400771a.pdf

Chlorhexidine Varnish may Prevent Dental Caries in Children and Adolescents.
Reference: J Evid Based Dent Pract. 2011 Jun;11(2):84-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21605831

Essential Oil Mouthwash (EOMW) may be Equivalent to Chlorhexidine (CHX) for Long-Term Control of Gingival Inflammation but CHX Appears to Perform Better Than EOMW in Plaque Control
Reference: Journal of Evidence-Based Dental Practice Volume 11, Issue 4 , Pages 171-174, December 2011
Abstract: http://www.jebdp.com/article/S1532-3382%2811%2900132-1/abstract?elsca1=etoc&elsca2=email&elsca3=1532-3382_201112_11_4&elsca4=dental

Chlorhexidine mouthwash reduces plaque and gingivitis
Reference: Evidence-Based Dentistry (2013) 14, 17–18
Abstract: http://www.nature.com/ebd/journal/v14/n1/abs/6400915a.html?WT.ec_id=EBD-201303

Caries prevention - little evidence for use of chlorhexidine varnishes and gels.
Reference: Evid Based Dent. 2015 Jun;16(2):43-4.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26114784

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